Must admit as I have got older weight has become a major factor in deciding what gear I now own. Not long ago I was happily walking around with a 1DX2, a 600mm f4 Mk2 and a Gitzo tripod with a Wimberley attached. An operation on my spine dictated the need to think again.
The R5 and the 100-500 have been a revelation. I sold the 600mm and the 1DX2 but hung on to both my 500mm f4Mk2 and the tripod set up although I rarely use them. The new mirrorless set-up is so lightweight I don't even need a tripod anymore, well not for the time being anyway. I'm heading towards 72 so I wonder at what stage I'm going to start having to think again but at the moment it's certainly not even on the horizon.
