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Something I've learned over the years that often gets missed is high ISO produces more noise in low light than the same high ISO in good light. This is because the signal to noise ratio is higher in good light irrespective of the ISO setting.  You can take a shot at ISO 6400 and the same shot when the sun coms out at a faster shutter speed with the same ISO setting and both correctly exposed and the noise will be much less with the sun out. This may seem obvious but it has led to me using high ISO on sunny days to get the fast shutter speed for say BIF without worrying so much about noise.