Yes.
I did some testing a couple of weeks ago.
Since getting the R5 I had noticed a real slowdown in Lightroom in terms of performance, despite using 2 decent specced machines:
2017 5K Retina 27 inch iMac - quad core i7 with 40GB RAM
2019 16 inch MacBook Pro - quad core I9 with 64GB RAM
I'd done some tests and found that uninstalling all of the Creative Cloud Apps (just leaving the actual apps installed, Lightroom Classic, Photoshop and Premiere Pro), that performance has picked up considerably.
I also did some export tests using CRAW and RAW files. I found CRAW consistently exports at 33% quicker, despite me not being able to see any difference in image quality or dynamic range, now I'm sure there will be but I can't see it with my eyes.
According to Canon, CRAW (or compressed RAW) uses a lossy-compression algorithm so some data is binned off to reduce file size, however I've been unable to find any noticeable difference at the moment.
RAW - my files sizes generally tend to be up to 60MB
and when I switch to CRAW the files sizes are considerably smaller.
So I know something has to be compromised but I can't see any difference.
So in summary, using CRAW has massively sped up my workflow, smaller file sizes and I can see no discernible difference in image quality or dynamic range.